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Can Prenatal Vitamins Reduce the Risk of Birth Defects?

The role of a prenatal vitamin is to support the healthy growth and development of growing babies, and minimizing the risk of birth defects is front and center. Research is clear that adequate amounts of specific nutrients–folate and choline chief among them–play a significant role in helping to prevent major birth defects in the developing spine and brain, such as spina bifida and anencephaly. Of course, it’s not the nutrients alone that are important, but the forms and amounts they take. So let's get into specifics, shall we?

Key Takeaways

  • Women hoping to become pregnant should get sufficient amounts of folate before and during pregnancy to support proper spinal and brain development.
  • Men benefit from high-quality nutrients prior to conception to support and promote healthy sperm with fewer DNA abnormalities, which are associated with recurrent miscarriage in their partners.
  • Experts advise couples to begin prenatal vitamins at least six months before conception to support fertility and lay the groundwork for a healthy pregnancy.
  • Choline rivals folate for reducing the risk of spinal, brain, and neural tube defects, but it’s lacking in many major prenatal vitamin formulations.
  • Vitamin D and iodine are often overlooked in sufficient amounts, despite their importance during pregnancy.
  • Beyond prioritizing specific nutrients, it’s important to look for effective dosing and bioavailable forms to ensure absorption.

Folate & Choline

When it comes to minimizing the risk of birth defects, folate gets the most attention–for good reason! A daily dose of at least 600 mcg of this essential B vitamin during the preconception stage and in the earliest weeks of pregnancy helps support proper brain and spinal development, and the timing here is key. So much critical development happens in the earliest stages of pregnancy, often before women realize they’re pregnant, and ensuring that you’re building up the vitamin reserves means you can better protect your growing baby from day one.

Beli-prenatal-vitamins

That’s one of the reasons experts recommend couples planning to become pregnant begin prenatal vitamins early–ideally six months before conception. Doing so supports fertility in men and women, which increases the chances of a successful conception, pregnancy, and healthy baby. Key micronutrients during this timeframe can drive conception for men and women alike, so prenatal vitamins like Beli for Women and Beli Vitality for Men are an important part of a healthy lifestyle as you make plans to become pregnant.

While it’s not as well-known, choline rivals folate in terms of reducing the risk of birth defects in the brain, spinal cord, and neural tube. Data also suggests that it has a role in better brain and cognitive outcomes, from faster information processing speeds to improved visual memory and attention spans. In fact, research suggests that maternal choline intake affects a child’s linguistic ability up to age seven, and possibly even longer. One study found that low maternal choline intake of less than 290 mg per day doubles the risk of having a baby with a neural tube defect. And it’s not the kind of thing you can make up later. According to Dr. Taylor Wallace, America’s Favorite Food Scientist and an expert on choline, “subsequent repletion of a nutrient like choline outside of the first 1,000 days window may not compensate for the detriment due to nutrient deficiency or inadequacy."

Many of the most popular prenatal vitamins on the market don’t include sufficient amounts of choline, despite the importance this B vitamin plays. It was recognized as an essential nutrient in 1998 by the National Academy of Medicine, and experts recommend a daily amount of 450 mg before and during pregnancy, and 550 mg for nursing mothers.

Other Key Nutrients to Reduce the Risk of Birth Defects

Your needs (and your growing baby’s) don’t stop at folate and choline. Vitamin D is another biggie, and like choline, it’s often overlooked. According to the American Pregnancy Association, “It is unlikely your prenatal vitamin provides enough vitamin D. A recent study found women taking 4,000 IU of vitamin D daily had the greatest benefits in preventing preterm labor/births and infections.” And that’s not all–women with higher levels of vitamin D also have a four-fold increase in becoming pregnant following IVF.

Low amounts of vitamin D in the average prenatal vitamin really is a problem. Mamas and their babies need sufficient amounts of vitamin D, and specifically D3, which studies show is more effective for raising vitamin D levels. Babies need it for healthy bone development and long-term health birth, while mamas-to-be benefit with low levels of vitamin D have a higher risk of preeclampsia, gestational diabetes, preterm delivery, postpartum depression, and higher incidences of miscarriage.

Of course, you can’t really talk about vitamin D3 without mentioning vitamin K2, which is essential for proper D3 absorption. That’s another important nutrient to scan for on the label of your prenatal vitamin bottle, along with iodine. Iodine deficiency during pregnancy is directly tied to a number of major, irreversible issues, including an increased risk of pregnancy loss and infant mortality. In fact, inadequate amounts of iodine during pregnancy have been the most significant preventable cause of brain damage since the beginning of the 19th century. The recommended daily amount of pregnancy is 220 mcg, which increases to 270 mcg for nursing mamas. Many prenatal vitamins only include 125 to 150 mcg in a serving, so make sure you’re double checking that label.

Understanding The Bigger Picture

Of course, nutrients in a high-quality prenatal vitamin, like Beli for Women, aren’t included simply because they minimize the risk of birth defects. Our formula is carefully calibrated to include the vitamins, minerals, and antioxidants that offer long-term benefits to moms and babies alike. And it’s not just the nutrients themselves that are important. It’s the amounts and forms of those nutrients that really move the needle. Effective dosing is key, and so is bioavailability. 

Beli for Women is a research-based prenatal vitamin formulated with those considerations in mind. We followed the latest guidelines and recommendations to ensure that you and your growing baby are getting the right nutrients in the right amounts with the most efficacious amounts, with an emphasis on purity and quality. It’s why our vegan vitamin D3 is sourced from lichen instead of sheep’s wool or fish liver oil. It’s why we use folate instead of folic acid, and VitaCholine, widely regarded as the gold standard for this particular nutrient. And it’s why we use Ferrochel, a chelated version of iron that’s easier on the tummy, and zinc from Albion TRAACs. Bonus–using higher-quality nutrients in every instance actually makes for a smaller serving size!

Surprise–Men’s Prenatals Can Help Reduce Birth Defects Too

The value of prenatal vitamins for men is rapidly becoming mainstream, and it’s something we here at Beli have been pushing for since we introduced Beli Vitality for Men almost 5 years ago! After all, that’s how we got our start–filling the enormous gap in the market for a science-aligned men’s prenatal vitamin that would ensure optimal sperm health. It’s settled science that a man’s fertility health affects his partner’s risk of miscarriage. The DNA blueprint for the placenta, which nourishes a growing baby during pregnancy, comes from sperm. Oxidative damage to sperm DNA, or DNA fragmentation, can have a profound effect on a pregnancy’s viability.

Just look at the research. A 2019 study found that the sperm of men whose partners had experienced recurrent miscarriages had significantly higher levels of DNA damage than men whose partners carried a pregnancy to term. “Now we realise both partners contribute to recurrent miscarriage,” said lead author Dr. Channa Jayasena, “we can hopefully get a clearer picture of the problem and start to look for ways of ensuring more pregnancies result in a healthy baby.”

That’s where the right nutrients come in. For men, fertility health is all about sperm health. Science has made it clear that the most common cause of sperm deficiencies is a shortage of nutrients during the sperm maturation cycle, and that proper prenatal nutrition is associated with higher-quality sperm and fewer DNA abnormalities. That means prioritizing nutrients that have been clinically proven to support sperm health, such as:

These six ingredients make up the Vitality Blend in Beli Vitality for Men, and we round out the formula with vitamins C, D3, E, B6, B12, methylated folate, zinc, and selenium, all of which benefit male fertility as well. And just like our women’s blend, the emphasis is on the right nutrients in the right forms and the right amounts, so that you know you’re getting exactly what you need to support your fertility for a successful conception, pregnancy, and baby.

The Bottom Line

When the plan is a baby, the last thing you and your partner should have to worry about is whether you’re getting all of the nutrients you both need, in the right amounts and most bioavailable forms, to minimize the risk of birth defects. And with Beli, we've got you covered. 

Additional Resources

The long, lazy days of summer aren’t just prime vacation days. Summer could actually be an especially fertile season, which may be of interest to couples who are interested in starting a family. If you’re angling for parenthood this summer, here’s what to know about the season of fertility.

Read More

The summer heat really can have a temporary effect on male fertility, so doing what you can to keep cool, especially if the goal is becoming a dad, is really important. Here are tips to keep you and the boys cool this summer.

Read More

If you’re no stranger to the telltale signs of seasonal allergies—sneezing, itching, nasal congestion, irritated eyes, the works—you’re likely familiar with antihistamines. When you’re actively trying to conceive, there’s more to understand about histamines, seasonal allergies and how it affects your fertility.

Read More

When the plan is a baby, but you’re having a hard time conceiving, it’s normal to start wondering why. While there can be a number of issues in play, one tends to be overlooked: sleep quality. Specifically, men who have the sleep disorder sleep apnea could be at greater risk of fertility issues. Now, new research is drawing a more definitive link between sleep apnea and male fertility. Let’s review.

Read More

Fact: You can’t look at a guy—or eyeball his semen sample, for that matter—and determine his fertility. It just doesn’t work that way. The only way to truly assess sperm health is with a semen analysis. But there are a few lifestyle choices and truths that may indicate whether a man’s sperm is healthy and happy. 

Read More

While PCOS can be a challenging condition to manage, natural supplements like inositol that are included in Beli Preconception Boost offer a beacon of hope. Inositol's ability to improve insulin sensitivity, hormone balance, and ovulatory function makes it a valuable tool in the PCOS management toolkit. 

Read More

The concern that hormonal contraception affects future fertility is making the rounds on social media again. But research continues to show that all that worry is for naught. While birth control doesn’t cause long-term fertility issues, it can mask them by creating an artificial cycle—something that’s important to understand.

Read More

While it’s lumped into the “bodily fluid” category, semen is a complex cocktail of compounds designed to support fertility. Like sperm quality, semen health can be influenced by lifestyle factors—an important realization for couples trying to conceive. From color to consistency, here’s what healthy semen looks like.

Read More

There’s a lot of chatter when it comes to male masturbation and what it says about a man’s fertility or whether it’s an issue when a couple is actively trying to conceive. And in the interest of clearing up the confusion, we’re taking a facts-based approach to the topic of men, masturbation and fertility.

Read More

For many of us, our twenties and even thirties are a time when the focus is on pregnancy prevention. And that’s okay! But even when the idea of motherhood is miles away there is tremendous value in understanding your fertility health and what you can do to support it during these young, carefree days.

Read More

We’re thrilled to introduce Beli Women Preconception, a complementary fertility supplement designed to support fertility health by promoting egg quality, supporting ovulation, balancing hormones, regulating your cycle and helping to manage symptoms of both PCOS and PMS.

Read More

Once a month, PMS symptoms make their unpleasant presence known. And while knowing what’s happening won’t make PMS magically disappear, it can help you manage symptoms by balancing hormones and supporting your reproductive health. Let’s review.

Read More

Raise your hand if you already know that you have a biological clock. From age 35 and beyond, there is a natural decline in testosterone and sperm quality. Just as people lose muscle strength, flexibility and endurance with age, sperm also tend to lose their "fitness" over the life cycle. But what does that mean—and does it really matter?

Read More

It’s an easy assumption, but you’re much better off thinking that every prenatal vitamin is wildly different in terms of composition, nutrient quality and, importantly, nutrient amount. Not only is that actually true, it puts you in the smart consumer mindset of understanding what matters in a prenatal vitamin—and why.

Read More

If you have endometriosis, you can already recite its lengthy list of pretty terrible symptoms. And the standard options for managing those symptoms — medications, hormone therapy, hormonal birth control, estrogen blockers, surgery —  aren’t always great. But there is evidence that a so-called “endometriosis diet” can help.

Read More

Men really do benefit from specialized nutrition in the form of a prenatal vitamin that’s formulated to support sperm health. Here’s what that looks like, and how specific nutrients can impact a man’s fertility health before fatherhood.

Read More

Shilajit is finally getting the credit it’s due, and we’re proud to point out that our proprietary formula was the very first to include this powerful Ayurvedic compound. Here’s why shilajit is rapidly becoming the darling of the male fertility world–and what you’re missing if you’re skipping it.

Read More

Ever wondered why men produce so much darn sperm, especially if only one of them will ultimately fertilize the egg? There are millions of sperm in normal ejaculate because it increases the likelihood that one will reach the egg and seal the deal. It begs the question, what exactly happens on the journey to the egg?

Read More

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Just as women’s bodies need to be prepared for pregnancy, men’s bodies need to be ready to contribute healthy sperm for conception. Nutrients are the foundation that support the normal structure and function of sperm and men's fertility health. Taking Beli’s male prenatal supplement is a proactive way to strategically fuel your body to optimize fertility contributing to your overall chances of conceiving and supporting a healthy pregnancy.  

Read More

Diet has been suggested to have an influence on the quality and function of human sperm. More specifically, the results of a randomised trial have shown that including nuts as a component of a regular diet improved the quality and function of human sperm.

Read More

A shot to the balls may be played for laughs on screen, but testicular impacts really aren’t a joke. Worse case scenario, getting hit in the balls can affect fertility thanks to complications like sexual dysfunction, low testosterone and other issues. Let's discuss.

Read More

With the New Year upon us, there are all kinds of articles and videos making the rounds with predictions of the Zodiac signs most likely to get pregnant in 2024. But here at Beli, we take a much more scientific approach to conception. Here are the top eight things people will do to get pregnant in 2024.

Read More

Research shows that the overall health of both biological parents during the preconception window plays a huge role in everything from conception to pregnancy health to the lifetime health of their baby. Luckily, there are simple steps you can both take to improve your health together.

Read More

When it comes to becoming parents, good habits really will take you where you want to go. Now, new science is giving us insight into exactly how long it takes to form those good habits. We're breaking down all the ways you can build healthy habits to boost your chances of conception. Think of it as life-hacking, but for grown-ups.

Read More

Preparing for a baby means doing everything in your power to nourish your fertility health. If you’re totally on board but wondering what that actually means, we’re breaking down the do’s and don’ts for planning a pregnancy.

Read More

Somewhere between the “let’s have a baby!” conversation and seeing those two pink lines, you’re going to end up researching prenatal vitamins. And trust us when we say you’re going to have a ton of options to wade through. Consider this your handy guide to the best prenatal vitamins for men and women in 2024.

Read More

Here at Beli, we’re working hard to raise awareness of the important role men play in the baby-making equation, which brings us to today’s topic of men’s preconception health and specifically, sperm health. Knowing what you’re working with can save you a lot of time, but is at-home sperm testing considered an important part of men’s preconception health? Let’s break it down.

Read More

The summer heat really can have a temporary effect on male fertility, so doing what you can to keep cool, especially if the goal is becoming a dad, is really important. Here are tips to keep you and the boys cool this summer.

Read More

If you’re no stranger to the telltale signs of seasonal allergies—sneezing, itching, nasal congestion, irritated eyes, the works—you’re likely familiar with antihistamines. When you’re actively trying to conceive, there’s more to understand about histamines, seasonal allergies and how it affects your fertility.

Read More

When the plan is a baby, but you’re having a hard time conceiving, it’s normal to start wondering why. While there can be a number of issues in play, one tends to be overlooked: sleep quality. Specifically, men who have the sleep disorder sleep apnea could be at greater risk of fertility issues. Now, new research is drawing a more definitive link between sleep apnea and male fertility. Let’s review.

Read More

Fact: You can’t look at a guy—or eyeball his semen sample, for that matter—and determine his fertility. It just doesn’t work that way. The only way to truly assess sperm health is with a semen analysis. But there are a few lifestyle choices and truths that may indicate whether a man’s sperm is healthy and happy. 

Read More

While it’s lumped into the “bodily fluid” category, semen is a complex cocktail of compounds designed to support fertility. Like sperm quality, semen health can be influenced by lifestyle factors—an important realization for couples trying to conceive. From color to consistency, here’s what healthy semen looks like.

Read More

There’s a lot of chatter when it comes to male masturbation and what it says about a man’s fertility or whether it’s an issue when a couple is actively trying to conceive. And in the interest of clearing up the confusion, we’re taking a facts-based approach to the topic of men, masturbation and fertility.

Read More

For many of us, our twenties and even thirties are a time when the focus is on pregnancy prevention. And that’s okay! But even when the idea of motherhood is miles away there is tremendous value in understanding your fertility health and what you can do to support it during these young, carefree days.

Read More

Raise your hand if you already know that you have a biological clock. From age 35 and beyond, there is a natural decline in testosterone and sperm quality. Just as people lose muscle strength, flexibility and endurance with age, sperm also tend to lose their "fitness" over the life cycle. But what does that mean—and does it really matter?

Read More

It’s an easy assumption, but you’re much better off thinking that every prenatal vitamin is wildly different in terms of composition, nutrient quality and, importantly, nutrient amount. Not only is that actually true, it puts you in the smart consumer mindset of understanding what matters in a prenatal vitamin—and why.

Read More

Men really do benefit from specialized nutrition in the form of a prenatal vitamin that’s formulated to support sperm health. Here’s what that looks like, and how specific nutrients can impact a man’s fertility health before fatherhood.

Read More

Shilajit is finally getting the credit it’s due, and we’re proud to point out that our proprietary formula was the very first to include this powerful Ayurvedic compound. Here’s why shilajit is rapidly becoming the darling of the male fertility world–and what you’re missing if you’re skipping it.

Read More

Ever wondered why men produce so much darn sperm, especially if only one of them will ultimately fertilize the egg? There are millions of sperm in normal ejaculate because it increases the likelihood that one will reach the egg and seal the deal. It begs the question, what exactly happens on the journey to the egg?

Read More

Just as women’s bodies need to be prepared for pregnancy, men’s bodies need to be ready to contribute healthy sperm for conception. Nutrients are the foundation that support the normal structure and function of sperm and men's fertility health. Taking Beli’s male prenatal supplement is a proactive way to strategically fuel your body to optimize fertility contributing to your overall chances of conceiving and supporting a healthy pregnancy.  

Read More

Diet has been suggested to have an influence on the quality and function of human sperm. More specifically, the results of a randomised trial have shown that including nuts as a component of a regular diet improved the quality and function of human sperm.

Read More

A shot to the balls may be played for laughs on screen, but testicular impacts really aren’t a joke. Worse case scenario, getting hit in the balls can affect fertility thanks to complications like sexual dysfunction, low testosterone and other issues. Let's discuss.

Read More

With the New Year upon us, there are all kinds of articles and videos making the rounds with predictions of the Zodiac signs most likely to get pregnant in 2024. But here at Beli, we take a much more scientific approach to conception. Here are the top eight things people will do to get pregnant in 2024.

Read More

Research shows that the overall health of both biological parents during the preconception window plays a huge role in everything from conception to pregnancy health to the lifetime health of their baby. Luckily, there are simple steps you can both take to improve your health together.

Read More

When it comes to becoming parents, good habits really will take you where you want to go. Now, new science is giving us insight into exactly how long it takes to form those good habits. We're breaking down all the ways you can build healthy habits to boost your chances of conception. Think of it as life-hacking, but for grown-ups.

Read More

Here at Beli, we’re working hard to raise awareness of the important role men play in the baby-making equation, which brings us to today’s topic of men’s preconception health and specifically, sperm health. Knowing what you’re working with can save you a lot of time, but is at-home sperm testing considered an important part of men’s preconception health? Let’s break it down.

Read More

The long, lazy days of summer aren’t just prime vacation days. Summer could actually be an especially fertile season, which may be of interest to couples who are interested in starting a family. If you’re angling for parenthood this summer, here’s what to know about the season of fertility.

Read More

If you’re no stranger to the telltale signs of seasonal allergies—sneezing, itching, nasal congestion, irritated eyes, the works—you’re likely familiar with antihistamines. When you’re actively trying to conceive, there’s more to understand about histamines, seasonal allergies and how it affects your fertility.

Read More

Choline is an overlooked essential nutrient in many prenatal vitamin formulas, and it's a major oversight. Here at Beli, we've been sounding the alarm for years and it's gratifying to see that the market is beginning to catch up. That's thanks in part to articles like "The 7 Best Choline Supplements for Pregnancy, According to a Prenatal Dietitian" from Parents. Spoiler: Beli for Women made the list.

Read More

While PCOS can be a challenging condition to manage, natural supplements like inositol that are included in Beli Preconception Boost offer a beacon of hope. Inositol's ability to improve insulin sensitivity, hormone balance, and ovulatory function makes it a valuable tool in the PCOS management toolkit. 

Read More

The concern that hormonal contraception affects future fertility is making the rounds on social media again. But research continues to show that all that worry is for naught. While birth control doesn’t cause long-term fertility issues, it can mask them by creating an artificial cycle—something that’s important to understand.

Read More

For many of us, our twenties and even thirties are a time when the focus is on pregnancy prevention. And that’s okay! But even when the idea of motherhood is miles away there is tremendous value in understanding your fertility health and what you can do to support it during these young, carefree days.

Read More

We’re thrilled to introduce Beli Women Preconception, a complementary fertility supplement designed to support fertility health by promoting egg quality, supporting ovulation, balancing hormones, regulating your cycle and helping to manage symptoms of both PCOS and PMS.

Read More

Once a month, PMS symptoms make their unpleasant presence known. And while knowing what’s happening won’t make PMS magically disappear, it can help you manage symptoms by balancing hormones and supporting your reproductive health. Let’s review.

Read More

It’s an easy assumption, but you’re much better off thinking that every prenatal vitamin is wildly different in terms of composition, nutrient quality and, importantly, nutrient amount. Not only is that actually true, it puts you in the smart consumer mindset of understanding what matters in a prenatal vitamin—and why.

Read More

If you have endometriosis, you can already recite its lengthy list of pretty terrible symptoms. And the standard options for managing those symptoms — medications, hormone therapy, hormonal birth control, estrogen blockers, surgery —  aren’t always great. But there is evidence that a so-called “endometriosis diet” can help.

Read More

With the New Year upon us, there are all kinds of articles and videos making the rounds with predictions of the Zodiac signs most likely to get pregnant in 2024. But here at Beli, we take a much more scientific approach to conception. Here are the top eight things people will do to get pregnant in 2024.

Read More

Research shows that the overall health of both biological parents during the preconception window plays a huge role in everything from conception to pregnancy health to the lifetime health of their baby. Luckily, there are simple steps you can both take to improve your health together.

Read More

Preparing for a baby means doing everything in your power to nourish your fertility health. If you’re totally on board but wondering what that actually means, we’re breaking down the do’s and don’ts for planning a pregnancy.

Read More